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Y NOW 2021: Realizing Autonomous Operations
Y NOW 2021: Realizing Autonomous Operations 07/11/2021

An autonomous operation is the ultimate destination in any digital transformation journey. Autonomous operations possess learning and adaptive capabilities that enable automated responses to emerging situations without human operator interaction. They can rapidly adapt to market disruptions and benefit from improved safety, higher reliability, increased efficiency, reduced costs, and expedited time-to-market. Y Now 2021 will showcase how to realize autonomous operations.

ARC Industry Forum 2021
ARC Industry Forum 2021 07/11/2021

Join us at the 25th Annual ARC Industry Forum to learn more about how digitizing factories, cities, infrastructure and supply chain will benefit technology end users and suppliers alike. Discover what Yokogawa and other industry players are doing today and what steps we are taking in our respective journeys.

High-Content Screening Reveals the Phenotypic Landscape of Intestinal Organoid Regeneration
High-Content Screening Reveals the Phenotypic Landscape of Intestinal Organoid Regeneration 07/11/2021

Image-based phenotypic screening relies on extraction of multivariate information from cells cultured in a large number of screened conditions. In this webinar, we explore the application of complex and biologically relevant model systems for drug screening, such as small intestinal organoids.

High-Content Screening Reveals the Phenotypic Landscape of Intestinal Organoid Regeneration

07/11/2021

Image-based phenotypic screening relies on extraction of multivariate information from cells cultured in a large number of screened conditions. In this webinar, we explore the application of complex and biologically relevant model systems for drug screening, such as small intestinal organoids.

We describe several processes used to infer regulatory genetic interactions and identify genes that regulate cell-fate transitions and maintain the balance between regeneration and homeostasis, unravelling previously unknown roles for several pathways, among them retinoic acid signalling.

We then characterise a crucial role for retinoic acid nuclear receptors in controlling exit from the regenerative state and driving enterocyte differentiation.

Finally, by combining quantitative imaging with RNA sequencing, we show the role of endogenous retinoic acid metabolism in initiating transcriptional programmes that guide the cell-fate transitions of intestinal epithelium and identify an inhibitor of the retinoid X receptor that improves intestinal regeneration in vivo.

Learning outcomes of this webinar:

  • Learn how to upscale, streamline and automate intestinal organoid handling
  • Learn how to image in complex three-dimensional (3D) model systems and how to approach big imaging datasets
  • Understand the basics of multivariate analysis on image-inferred features
  • Ask our expert speaker questions and benefit from their knowledge and guidance.

Bảng giá thiết bị hệ thống hội nghị truyền hình trực tuyến 2022


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